Beyond Blue

Ready for This? A Home Bipolar Test

Friday April 4, 2008

Categories: Mental Health

bipolar%20drug.jpg

Thanks once more to Lilit Marcus who is a fantastic story finder for me! Now that Larry has a job I'm recruiting readers who can forward me current events related to depression and bipolar disorder. Since I never seem to be able to read the dang paper before Eric disposes of it. (Remember, major clutter control going on in my home.)

Lilit sent me this fascinating AP story about a psychiatric geneticist at the University of California, San Diego, who is selling bipolar genetic tests over the Internet.

WHAT?

Here's a clip of the AP story that you can get to by clicking here.

Dr. John Kelsoe has spent his career trying to identify the biological roots of bipolar disorder. In December, he announced he had discovered several gene mutations closely tied to the disease, also known as manic depression.

Then Kelsoe, a prominent psychiatric geneticist at the University of California, San Diego, did something provocative for the buttoned-down world of academic medical research: He began selling bipolar genetic tests straight to the public over the Internet last month for $399.

His company, La Jolla-based Psynomics, joins a legion of startups racing to exploit the boom in research connecting genetic variations to a host of health conditions. More than 1,000 at-home gene tests have burst onto the market in the past few years.

The proliferation of these tests troubles many public health officials, medical ethicists and doctors. The tests receive almost no government oversight, even though many of them are being sold as tools for making serious medical decisions.

Health experts worry that many of these products are built on thin data and are preying on individuals' deepest anxieties.

"People are always rushing to the market on the basis of one or two studies," said Dr. Muin Khoury, director of the National Office of Public Health Genomics at the Centers for Disease Control and Prevention. "We have very little evidence that telling people their genetic information is going to make any difference."

Tests have become available claiming to help predict and diagnose everything from serious illnesses like cancer and Alzheimer's to athletic ability and a person's ideal diet. Psynomics' offering is one of the first psychiatric gene tests on the market.

Kelsoe, 52, acknowledges that bipolar disorder probably results from a combination of genetic factors and life experiences, and that the presence of these gene variations does not at all mean that someone will, in fact, develop the disease. He admits, too, that his findings about the genetic basis of the illness are far from complete.

But he said his test is a vital starting point toward moving away from the notoriously tricky practice of diagnosing bipolar disorder based purely on a person's behavior.
"The goal of this is to try and help doctors make an accurate diagnosis more quickly so the patient can be treated appropriately," Kelsoe said. "Anything is going to help, even if it just helps a little bit."

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Comments
Tricia
April 6, 2008 8:11 PM

Thanks Lisa,

A great site!

Gratefully,

Betty
April 8, 2008 11:54 AM

I have been going through some very hard personal depression. My daughter left for college this year. That in itself sparked my depressive moods and from October to now. I feel that I am fighting a losing battle within myself. Everyday, I start out trying to make myself feel a little better than the next but it is short lived. Throughout the days I can be okay and then within the hour I get the really really low sinking feeling and that I cannot seem to stop this. I was originally on Wellbutrin 300XL and Lexapro 20 mg but I am at the point that even the medicine was not helping. I have been to a new family physician and she has taken me off of those medications and I am not on 60 mg of Cymbalta but that is not helping. I have found out through my sisters and brother that my older sister is Bi-Polar, my mother was, and now my brother has been diagnoised with Bi-polar with Skizophrenic tendacies. Could my feeling so different from the past and my undying sad feelings be bi-polar to? Any help is appreciated.

Thank you,
Betty

Larry Parker
April 8, 2008 10:04 PM

Cosima is right, Therese -- we tried to get a discussion going on this on the BB social networking group but it didn't take.

I'll repeat what I said then -- this could be a godsend for diagnosis, if not for the fact that no one with bipolar would ever work or have insurance again once employers and HMOs get hold of the results ...

Lynne
April 9, 2008 9:26 AM

Larry, once again you hit the nail on the head about the "dangers of exposure". How can one seek treatment when you run the risk of being discredited as a "normal" human being? I think we are still a long ways from living in the light of day. It makes me however so much the more grateful for this blog! If not for BB ...my head might explode! (okay maybe a little too graphic.) I just feel the need to wear the mask of sanity a little too frequently these days.

Matt
May 27, 2008 3:10 AM

In response to Betty,
You are not too far off in thinking that you may be Bipolar. Bipolar disorder is closely related to both depression & mania. There is a fantastic Bipolar support organization called Bipolar Support Alliance. They are national and hold support and informational meetings in practically every city in the nation. The organization focuses on Bipolar Disorder and Depression since they are so closely linked. You can go to their website http://www.dbsalliance.org/index.html for info and meeting locations near you. With regards to your medication concerns, Wellbutrin has been known to actually increase and/or cause severe depression in youths and some adults. You may want to ask your doctor about Tegretol, Abilify, Depakote, Resperdal. These are all commonly administered and effective medications used in the treatment of Bipolar Disorder. I have found that the more you know about all the different treatments that are availble the better dicision you can make concerning your health. I have also found that some mental health professionals are influenced by pharmaceutical companies to push certain medications an not others. If your doctor is not listening to your concerns or is not open to your suggestions then my advice is to find one that will. May your burdens lighten and your life brighten. Peace.

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