It sounds like just another of those silly multiple warnings they put in commercials for medication, you know where they say, “Do not use if you are pregnant or standing near someone who might become pregnant.)

I was on mega doses of cipro for over 2 months in 1999.
I had problems with swollen knees and ankles but my Dr. told me I needed the cipro more than I needed sore knees.
I had 3 raging infections after hernia surgery and had to have the insision opened up and heal from the inside.
I didn’t have any problems with my tendons before the surgery but sure have had since. I am still having problems walking.
The instructions with the cipro said not to give to small children and older people so they gave it to me as I was 49. Guess I was older than I thought.
I really do hope that no onelse has these problems as it is very painful when your tendons pop when you are doing your usual daily activities. I bent over to pick up a piece of paper off the floor and the tendon in my left leg popped and the pain was awful. I didn’t go to the Dr. as I have no insurance so just got through the pain and it takes a long time to stop hurting.

I think the next time the doctor recommends cipro, I’m going to decline.

Death by sepsis is worse. The number of problems reported vs. the number of users seems fairly small. Just pay attention to the directions.
Mind you, thanks to overprescription and including fluoroquinones in animal feed, its effectiveness as an antibiotic of last resort is now greatly diminished.

I was on 2 rounds of Cipro for a spider bite and I am a Masters T&F athlete. I developed a slight achilles tear that was treated sucessfully by my physical therapist.
I now say I am allergic to Cipro.

Took Levaquin in January 2005, for persistant sinus infection that was not responding to Aithro max (allergic to other antibiotics). July 2005 left foot/ankle started swelling. No injury EVER to my feet. Never extreme athlete. Extremely healthy and fit – not over weight. No other connective tissue disorder or broken bones or pulled muscles EVER. Foot/ankle swelling became painful. Since there was no injury, doctor checked for gout, arthritis, auto-immune, blood clot, stress fracture. Pain & swelling persisted for several weeks, woke up early one Sunday morning – walking down hallway at home, felt snap like rubber band breaking inside my foot /shin/ankle are, took another step, snap again. My foot and ankle were not able to support me , I “scuttled” (like a crab) in a sitting position, back wards to a chair, used my arms to lift myself into chair. My husband took me to a weekend clinic of my doctors group. On Monday, got an MRI (early August)- finally (I think one should have been done earlier – but I had an HMO Health Net insurance- and I feel like there were tons of delays waiting for authorization to see specialists (orthopedic, rheumatologist) and the less expensive diagnostic tests were given precedence – even though it was quite evident it was a soft tissue /connective tissue problem. MRI indicated to breakdon of balancing tendons, Orthopedic surgeon said he coudl not do surgery until Novemeber – and I MUST stay off my foot until then. It was a 4 or 5 hour operation, 5 days in hospital and 5 months of casts (cast changes & X-rays every few weeks) Total healing time projected by surgeon = 2 yrs. I teach Art at the college level I had to teach from a wheel chair for 2 semesters. Had to reserve all my energy to teach (I am adjunct faculty plus self employed artist) – spent the rest of every waking hour in a chair with my foot elevated for MONTHS.I am an artist Still have some pain & swelling, need prescription NSAID. Had tendon transplant (tendon taken from another part of same foot) had to have my heel cut and moved 8 mm and screwed back together to realign my ankle so it would bear weight again. Generally a huge nightmare, could not work in my studio = loss of income from my art work.

My husband took Cipro in 1998. Around 11 months after, his tendons started to rupture in 1999. Also 1 in 2000 & another in 2001. The 1 in 2001 was a quadriceps muscle that tore in half midway up his right thigh. I know some people will think that it couldn’t possibly be the Cipro because it was so long “after” taking it that the ruptures began. Well, in 2004 he took CiproXR. This was the second time he had ever taken a Cipro medicine. Around 11 months “after” the rupturing began again. This time he had 3 ruptures that involved both his arms. He became disabled after taking CiproXR. Tendonitis & ruptures aren’t the only adverse reactions. Here are a list of the adverse reactions he has: insomnia, panic attacks, rectal bleeding, involuntary movement of arms & legs especially trying to rest, neuropathies in both legs & arms, severe headaches & migraines caused by jumps in high blood pressure, severe depression, suicidal thoughts & acts, psychotic episodes, back spasms, muscle & joint pain & a few more. These began after taking Cipro & became far worse after taking CiproXR. There was also angioedema of the lip(terribly swelled left bottom corner of his lip that lasted only a few days) both times, rash that looked like tiny ant bites around his ankles after Cipro, & a rash that had bigger sores with dark centers in patches on his body after CiproXR. The doctors never knew what caused his 6 ruptures. No one ever suspected all these adverse reactions were connected. We won’t take any quinolones again.

I was a healthy 42 year old male who took Levaquin for a sinus infection. The same day as the Black Box Warning was issued; I was having my third tendon reattachment surgery. I have to wait at least 6 weeks before I can undergo yet a fourth tendon rupture reattachment. At least it takes my mind of the Achilles Tendinopathy, joint pains, headaches, uncontrolled muscle twitching etc. I consider myself one of the lucky ones since so far it has not affected my kidneys, liver, heart, eyes and other side effects that many are dealing with from this class of drugs. I would urge a real journalist to take the time and look at the real number of cases. The Fda numbers are misleading. The clinical data coming from other counties are showing much higher rates of tendon ruptures and other life threatening side effects.

I took Avelox three years ago and have experienced severe pain in my feet ever since. Sometimes the pain in so bad I cant sleep. Looking at my feet one can see the tendons actually spasm. I would love to file a lawsuit against the manufacturers of Avelox. Has anyone have any experience with lawsuits in this area?

I really appreciate these inputs but what I don’t understand is no one has mentioned how long and how much of a dose they took and how old they were. I think this is very important for people like me who search online to find some facts. I have an infection that seems to only respond to these antibiotics. I am out of luck and have to use cipro 500 mg twice a day for 6 weeks. If I don’t my nose will be deformed as I get older due to the infection in my sinuses. I decided to try this even though the side affects are sounding worse.
I am a 30 year old male and all these complaints and descriptions are only making me paranoid and nervous. I can’t sleep properly mainly because I can’t help reading these comments online that are scaring the living “cr4p” out of me. Please people next time you post comments be clear and explain everything why you took the med and your age, dosage and details like that so we can compare our situations.
My ENT has waited for over a year because he claims cipro or levaquin are the only drugs that the bacteria is responding to. So I trust him please I beg you next time don’t post these scary experiences without proper data. Every person might have response differently atleast if we have all the information we can decide. I have no option but to try this drug and this will be the last time I try.

I was 30 years old when I took 3 days of 500mg Levaquin. Experienced worst headache of my life, followed by over a year of muscle pain, joint pain and instability, weak tendons and muscle, trigger points, recurrent infections, skin rashes, weight loss, muscle atropohy , etc. I have done a year of research on Levaquin. DO NOT take this drug under any circumstances. There is ALWAYS another option.

I’m 38 yrs. Old. I was prescribed levaquin 500 MG for a sinus infection to take once per day for 21 days. The Allergist doctor said if your joints start aching, like in your knees call me and I’ll change the prescription, don’t try to work through it. I didn’t think it to be a big deal. After a week into taking Levaquin my hand and arm would go numb in the middle of the night. I thought maybe I was sleeping on it for too long and it went numb. After about 4 more days my knees and lower back started aching and all the way up the back of my calf where the achillies tendon is ..is extremely tender. I called the doctor and asked to have the presciption changed. The doctor never told me the damage this drug can cause to your tendons. He just said if you have aching in your joints, like arthritis. What makes it worse is I went to see an ENT about 10 days after taking the medicine because my sinus’ still didn’t show signs of improving. I told the ENT that I was taking Levaquin. He said it was a good medicine and to keep taking it. Even after I wrote down and told him my elbow joints were aching, had numbness in hand and pain in back of leg. I haven’t taken the medicine for 2 days but the pain up the back of my calf and aching in my knees has not improved.

I had 4 courses of Keflex / Cephalexin last year, and several months later experienced extreme tendinitis in both arms. Not more than 30 days later I ruptured my biceps tendon while picking up a computer.
As anyone heard of ruptures related to Keflex / Cephalexin?

If you have been or are currently using the Johnson & Johnson and Ortho-McNeil antibiotic Levaquin, you need to be aware that Levaquin has been linked to dozens of cases of serious tendon injuries and ruptures.  This site has a lot of good information on the problem: http://www.yourlawyer.com/topics/overview/levaquin

I took levaquin for 3 weeks after having the flu. A few days after I stopped, i was feeling better so i went to the gym. I felt something pop on my arms. It turns out I ruptured the tendon in my right arm, and almost in the left arm too. I am now scheduled for surgery, all for taking a medication. I found out more on a blog about levaquin, levaquinblog.com that these drugs can actually do what the doctor said they did.

This is real scary stuff. Thanks for posting your experience. And James, that link has some real useful information on it.

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